Outlook could not create the work file, error when you start Outlook

Symptoms

When you start Microsoft Outlook, you receive the following error message:

Cause

This problem occurs when the Cache string value in the registry doesn't point to a valid directory.

Resolution

Warning Serious problems might occur if you modify the registry incorrectly by using Registry Editor or by using another method. These problems might require you to reinstall the operating system. Microsoft cannot guarantee that these problems can be solved. Modify the registry at your own risk.


To resolve this issue follow these steps.

1. Exit Outlook.
2. Start Registry Editor. To do this, use one of the following procedures, as appropriate for your situation:
• Windows 10, Windows 8.1 and Windows 8: Press Windows Key+R to open a Run dialog box. Type regedit.exe and then press OK.
• Windows 7 or Windows Vista: Click Start, type regedit.exe in the search box, and then press Enter.
3. Locate and then click the following subkey:

HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\User Shell Folders

4. Right-click the Cache key, and then click Modify.
   
   Note The Cache string value varies, depending on your version of Windows.
   
   Windows 10, or Windows 8.1

DWORD: Cache
Type: REG_EXPAND_SZ
Data: %USERPROFILE%\AppData\Local\Microsoft\Windows\INetCache

Windows 8, Windows 7, or Windows Vista

DWORD: Cache
Type: REG_EXPAND_SZ
Data: %USERPROFILE%\AppData\Local\Microsoft\Windows\Temporary Internet Files

Windows XP

DWORD: Cache
Type: REG_EXPAND_SZ
Data: %USERPROFILE%\Local Settings\Temporary Internet Files

5. On the File menu, click Exit to exit Registry Editor.